Anthelmintic effect of four extracts obtained from Caesalpinia coriaria foliage against the eggs and larvae of Haemonchus contortus

Abstract To investigate the in vitro anthelmintic efficacy of dividivi (Caesalpinia coriaria), a traditional medicinal plant used Central America and northern part South America, extracts from foliage this were subjected to egg hatching test (EHT) larval exsheathment inhibition (LEIT), against Haemonchus contortus. Four different evaluated: acetone-water (AW), methanol-water (MW), acetone-water-dichloromethane (AWD) methanol-water-dichloromethane (MWD). The concentrations for EHT LEIT tests ranged 500 4000 µg mL-1 six repetitions per concentration. effective (EC50) calculated using Probit analysis. EC50 2947.0, 3347.0, 3959.6 4538.7 MWD, MW, AW AWD, respectively. 2883.4, 5927.4, 9876.3 9955.4 AW, MWD methanol most inhibiting eggs, while acetone showed exsheathment. This study explains importance that C. coriaria has as American countries.